Progress on the pathogenesis of plastic bronchitis caused by respiratory viruses in children / 国际儿科学杂志

ABSTRACT

Plastic bronchitis(PB)is a rare acute severe respiratory disease in children aged 2-12 years old.The causes of PB include heart disease, hereditary hemoglobin molecule dysfunction disease, lung disease, lymphatic system disease, etc.Among them, lung disease is commonly associated with infection.At present, most of the reported cases in China are post infection PB, with diverse clinical manifestations and varying degrees of severity.The pathogenesis is currently unclear.Existing research suggests that the pathogenesis of PB is related to airway infections, inflammatory reactions, and immune dysfunction.This article reviews the research progress on the pathogenesis of respiratory virus induced PB in children, with the aim of improving clinical doctors′ understanding of PB.