Obstructive sleep apnea and vascular cognitive impairment: role of blood-brain barrier impairment / 国际脑血管病杂志

ABSTRACT

Obstructive sleep apnea (OSA) is a sleep disorder characterized by recurrent upper respiratory tract obstruction, sleep fragmentation, and hypoxia during sleep. This disease often leads to cognitive, emotional, and memory related neurological damage, and its mechanism is closely associated with the disruption of the blood-brain barrier (BBB). This article mainly discusses the relationship between BBB damage caused by OSA and vascular cognitive impairment (VCI), as well as the role of early prevention, intervention, and repairing BBB on reducing VCI.