Dose pulmonary puncture biopsy increase the risk of pleural recurrence and air space spread of tumor in patients with stage Ⅰ non-small cell lung cancer? / 介入放射学杂志

ABSTRACT

In recent years,with the increasing proportion of pulmonary nodules,preoperative percutaneous lung puncture biopsy and bronchoscopic biopsy have received more and more attention.A large amount of clinical evidences indicate that lung puncture biopsy of stageⅠnon-small cell lung cancer(NSCLC)is safe and feasible.However,due to the histological characteristics of pulmonary ground-glass nodule(GGN),puncture biopsy of GGNs is more likely to cause bleeding and cough,and the tumor cells may be implanted along the alveolar wall or needle tract under the impact of blood flow or airflow,leading to the pleural recurrence and tumor spread through air spaces(STAS),when compared with puncture biopsy of solid nodules.Therefore,percutaneous lung puncture biopsy should be carefully adopted,especially for the patients who have subpleural nodules with visceral pleura invasion and lymphocyte infiltration.(J Intervent Radiol,2024,32:7-11)