Advances in the effect of inflammatory factors on immune mechanism of aplastic anemia / 新乡医学院学报
Journal of Xinxiang Medical College
; (12): 298-301, 2024.
Article
ي Zh
| WPRIM
| ID: wpr-1022689
المكتبة المسؤولة:
WPRO
ABSTRACT
The pathogenesis of aplastic anemia(AA)is complex and associated with hematopoietic stem cell defect,abnormal bone marrow microenvironment,immune dysfunction,and somatic mutation,in which the immune mechanism plays an important role.This article reviews the pathogenesis of AA from the following aspects:regulatory T cell reduction,hematopoietic stem cell reduction caused by factor-related apoptosis/factor-related apoptosis ligand signaling pathway,aberrant target gene expression induced by inflammatory factor-stimulated microRNAs,and regulatory T cell dysfunction,so as to provide ideas and methods for clinical practice.
النص الكامل:
1
الفهرس:
WPRIM
اللغة:
Zh
مجلة:
Journal of Xinxiang Medical College
السنة:
2024
نوع:
Article