Mechanism of Ki-67 in lung cancer and related progress in research on radiomics / 中国医科大学学报

ABSTRACT

Radiomics is a new diagnostic and treatment technology,which can be employed to extract high-throughput radiomics features from CT,MR,and PET images and screen features closely related to diagnostic and treatment purposes,so as to accurately predict tumor or disease classification,prognosis,or genomic changes.Ki-67 is a type of nuclear protein,which is present only in nuclei of proliferative and dividing cells but not in those of quiescent phase cells;hence,it can be used as a predictor of cell proliferation and has been proven to be closely related to prognosis of lung cancer.This article reviews the mechanism and progress in radiomics research related to Ki-67 in lung cancer.