Methods for the morphological and functional evaluation of microvascular damage in systemic sclerosis
The Korean Journal of Internal Medicine
; : 1-5, 2015.
Article
ي En
| WPRIM
| ID: wpr-106143
المكتبة المسؤولة:
WPRO
ABSTRACT
Systemic sclerosis is a connective tissue disease characterized by alterations in microvascular structure and function. In these patients, numerous studies have demonstrated a relationship between capillary morphology and peripheral blood perfusion. Nailfold videocapillaroscopy reveals the peripheral microvascular morphology and thus allows classification and scoring of capillary abnormalities with respect to different microangiopathy patterns (early, active, and late). Laser Doppler flowmetry and laser speckle contrast analysis can be used to estimate cutaneous blood flow through microvessels and to assess and quantify blood perfusion at peripheral sites. These two methods are also used to identify changes in digital blood perfusion after the infusion of vasodilators.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Regional Blood Flow
/
Scleroderma, Systemic
/
Skin
/
Vasodilator Agents
/
Video Recording
/
Blood Flow Velocity
/
Predictive Value of Tests
/
Laser-Doppler Flowmetry
/
Microscopic Angioscopy
/
Microvessels
نوع الدراسة:
Prognostic_studies
المحددات:
Humans
اللغة:
En
مجلة:
The Korean Journal of Internal Medicine
السنة:
2015
نوع:
Article