Pretreatmet with 5% lidocaine patch reduces cannula-induced and propofol-induced pain: a randomized, double-blind, placebo-controlled study / 대한마취과학회지
Korean Journal of Anesthesiology
; : 468-473, 2016.
Article
ي En
| WPRIM
| ID: wpr-123011
المكتبة المسؤولة:
WPRO
ABSTRACT
BACKGROUND:
The purpose of this study was to determine the efficacy of 5% lidocaine patch in reducing propofol-induced pain and cannula-induced pain.METHODS:
In a randomized, double-blind study, 126 patients were divided into one of three groups pretreatment with a 5% lidocaine patch (Lidotop®) and premixed 2 ml of normal saline with 1.5 mg/kg of 1% propofol (Group A); pretreatment with a placebo patch and premixed 2 ml of normal saline with 1.5 mg/kg of 1% propofol (Group B); or pretreatment with a placebo patch and premixed 2 ml of 2% lidocaine (40 mg) with 1.5 mg/kg of 1% propofol (Group C) for induction of anesthesia. Pain severity was evaluated on a four-point verbal rating scale during intravenous cannulation, propofol injection, and 24 h after the operation (recall).RESULTS:
Eighteen patients (47.4%) in Group A complained of cannula-induced pain compared with 35 (94.6%) in Group B and 36 (94.7%) in Group C (P < 0.001). Group A patients showed significantly lower incidence of propofol-induced pain and recall of propofol-induced pain compared with Group B (P < 0.001 and P = 0.01), whereas there was no difference compared with Group C.CONCLUSIONS:
Preoperative transdermal administration of 5% lidocaine patch is an effective and simple method in reducing propofol-induced pain as well as cannula-induced pain.Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Administration, Cutaneous
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Catheterization
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Propofol
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Double-Blind Method
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Incidence
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Anesthesia
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Lidocaine
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Methods
نوع الدراسة:
Clinical_trials
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Incidence_studies
/
Prognostic_studies
المحددات:
Humans
اللغة:
En
مجلة:
Korean Journal of Anesthesiology
السنة:
2016
نوع:
Article