The Prognostic Value of the Preoperative Lymphocyte Count in Patients with Gastric Cancer
Journal of the Korean Gastric Cancer Association
; : 26-30, 2009.
Article
ي Ko
| WPRIM
| ID: wpr-15703
المكتبة المسؤولة:
WPRO
ABSTRACT
PURPOSE: The aim of this study was to evaluate the prognostic value of the peripheral blood lymphocyte count before surgery in those patients with gastric cancer. MATERIALS AND METHODS: The study group was comprised of a series of 1,054 patients who underwent curative gastrectomy. The appropriate lymphocyte count cutoff value was determined. The prognostic factors were evaluated by univariate and multivariate analyses. RESULTS: The lymphocyte count cutoff value was 1,500/ul. The patients were classified into two groups: Group A had a lymphocyte count > or =1,500/ul (n=765) and Group B had a lymphocyte count <1,500/ul (n=289). There were statistically significant differences between the groups according to their age (P<0.001), the tumor stage (P=0.038) and the tumor size (P<0.001). The 5- and 10-year survival rates of Group A were 80.1% and 76.6%, respectively and those of Group B were 72.4% and 63.5%, respectively (P=0.002). When multivariate analysis was performed by the Cox proportional hazards model, the lymphocyte count was not an independent prognostic factor. CONCLUSION: Although the prognosis of patients with a high lymphocyte count was better than that of the patients with a low lymphocyte count, our results did not support using the preoperative peripheral blood lymphocyte count as an independent prognostic factor for patients with gastric cancer.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Prognosis
/
Stomach Neoplasms
/
Lymphocytes
/
Proportional Hazards Models
/
Multivariate Analysis
/
Survival Rate
/
Lymphocyte Count
/
Gastrectomy
نوع الدراسة:
Prognostic_studies
المحددات:
Humans
اللغة:
Ko
مجلة:
Journal of the Korean Gastric Cancer Association
السنة:
2009
نوع:
Article