Association between Cerebral Amyloid Deposition and Clinical Factors Including Cognitive Function in Geriatric Depression: Pilot Study Using Amyloid Positron Emission Tomography
Clinical Psychopharmacology and Neuroscience
; : 378-382, 2016.
Article
ي En
| WPRIM
| ID: wpr-160422
المكتبة المسؤولة:
WPRO
ABSTRACT
The purpose of this study was to explore the relationship between cerebral amyloid deposition and overall clinical factors including cognitive functions in geriatric depression by using 18F-florbetaben positron emission tomography. Thirteen subjects aged over 60 years who had a history of major depressive disorder and also had subjective memory complaint were included. Of all subjects, 3 subjects judged as amyloid positive, and the others judged as amyloid negative. Their memory, visuospatial functions and attention abilities were negatively correlated with amyloid deposition in specific brain regions, but their language and recognition abilities were not correlated with any region. The amyloid deposition of the whole brain region was significantly negatively correlated with immediate memory.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Attention
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Brain
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Pilot Projects
/
Cognition
/
Plaque, Amyloid
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Positron-Emission Tomography
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Depression
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Depressive Disorder, Major
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Electrons
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Alzheimer Disease
اللغة:
En
مجلة:
Clinical Psychopharmacology and Neuroscience
السنة:
2016
نوع:
Article