Gender Differences in the Association between Depressive Symptoms and Carotid Atherosclerosis among Middle-Aged and Older Koreans: The Namwon Study
Journal of Korean Medical Science
; : 1507-1513, 2014.
Article
ي En
| WPRIM
| ID: wpr-161118
المكتبة المسؤولة:
WPRO
ABSTRACT
We investigated the association of depressive symptoms with carotid intima-media thickness (IMT) and plaques in the general Korean population. A total of 7,554 Korean males and females aged 45-74 yr who were free from cardiovascular diseases were included in the analyses. Depressive symptoms were assessed by the Center for Epidemiologic Studies Depression Scale (CES-D). Subjects with a score of > or =16 were classified as having clinically significant depressive symptoms. Carotid ultrasonography was used to measure mean carotid IMT (C-IMT) and to determine the presence of plaques. A significant association between depressive symptoms and C-IMT was observed only in females. After adjustment for established cardiovascular risk factors, females with depressive symptoms had significantly greater C-IMT than females without depressive symptoms (mean difference 0.011+/-0.004 mm; 95% confidence interval, 0.003-0.019 mm). Compared with controls, the fully adjusted risk of females with depressive symptoms for abnormal C-IMT (> or =1.0 mm) was significant (odds ratio, 1.63; 95% confidence interval, 1.16-2.30). No significant association between depressive symptoms and carotid plaques was observed in either gender. This study shows a significant association between depressive symptoms and C-IMT in middle-aged and older females.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Psychiatric Status Rating Scales
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Alcohol Drinking
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Carotid Artery Diseases
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Smoking
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Odds Ratio
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Sex Factors
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Cross-Sectional Studies
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Surveys and Questionnaires
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Risk Factors
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Asian People
نوع الدراسة:
Diagnostic_studies
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Etiology_studies
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Observational_studies
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Prevalence_studies
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Risk_factors_studies
المحددات:
Aged
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Female
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Humans
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Male
البلد/الأقليم حسب الموضوع:
Asia
اللغة:
En
مجلة:
Journal of Korean Medical Science
السنة:
2014
نوع:
Article