Double primary lung adenocarcinoma diagnosed by epidermal growth factor receptor mutation status / 영남의대학술지
Yeungnam University Journal of Medicine
; : 270-274, 2017.
Article
ي En
| WPRIM
| ID: wpr-174339
المكتبة المسؤولة:
WPRO
ABSTRACT
A nodular density was detected on a chest radiograph taken from a 57-year-old Korean woman who was visiting a hospital for a routine check. Chest computed tomography revealed a 4.8 cm lobulated mass in the right lung and another focal nodular lesion in the left lung; biopsies of both lungs revealed adenocarcinoma. We conducted DNA sequencing and peptide nucleic acid clamping to investigate the potential double primary lung cancer. The results verified that the mass in the right lung had a mutation in the epidermal growth factor receptor, whereas the nodule in the left lung had a wild-type sequence, showing that these two were genetically different cancers from one another. Thus, we demonstrate that genetic testing is useful in determining double primary lung cancer, and we herein report on this case.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Thorax
/
Biopsy
/
Radiography, Thoracic
/
Adenocarcinoma
/
Genetic Testing
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Sequence Analysis, DNA
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Constriction
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Diagnosis, Differential
/
Epidermal Growth Factor
/
ErbB Receptors
نوع الدراسة:
Diagnostic_studies
/
Prognostic_studies
المحددات:
Female
/
Humans
اللغة:
En
مجلة:
Yeungnam University Journal of Medicine
السنة:
2017
نوع:
Article