A Case of Myasthenia Gravis after Allogeneic Bone Marrow Transplantation
Journal of the Korean Neurological Association
; : 60-61, 2001.
Article
ي Ko
| WPRIM
| ID: wpr-176466
المكتبة المسؤولة:
WPRO
ABSTRACT
A 38-year-old woman, affected by chronic myeloid leukemia, received a BMT from his HLA identical brother. A mild acute graft-versus-host disease (GVHD) developed during the first month after the BMT. A typical clinical and electrophysiological feature of myasthenia gravis (MG) developed 3 months after the BMT requiring medication with pyridostigmine and steroids. Laboratory findings including acetylcholine receptor antibody and other autoantibodies were negative. MG is a well-characterized autoimmune disease which, on rare occasions, is also diagnosed as chronic GVHD after BMT. We report a first case of MG during an acute GVHD period. Since the patient had a myasthenic symptom during an acute GVHD period and no evidence of antibody mediated autoimmunity, this is likely to be an immune complication of acute GVHD. (J Korean Neurol Assoc 19(1)60~61, 2001
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Pyridostigmine Bromide
/
Autoantibodies
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Autoimmune Diseases
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Steroids
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Bone Marrow
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive
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Acetylcholine
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Autoimmunity
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Bone Marrow Transplantation
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Siblings
المحددات:
Adult
/
Female
/
Humans
اللغة:
Ko
مجلة:
Journal of the Korean Neurological Association
السنة:
2001
نوع:
Article