Transient Increase in Intrathoracic Pressure as a Contributing Factor to Cardioembolic Stroke

ABSTRACT

BACKGROUND: The hemodynamic effects of increased intrathoracic pressure (ITP) have been the focus of many investigations. However, very little is known about the effects of elevated ITP on the occurrence of stroke. CASE REPORT: Four young patients with a cardioembolic source of stroke were examined. In all cases the stroke was preceded by an increase in ITP that occurred during coughing, vomiting, or sexual intercourse. CONCLUSIONS: We suggest that cardioembolic stroke is facilitated by situations in which ITP is elevated.