Pulmonary Thromboembolism Caused by PROS1 Gene Mutation / 계명의대학술지
Keimyung Medical Journal
; : 94-98, 2014.
Article
ي Ko
| WPRIM
| ID: wpr-191854
المكتبة المسؤولة:
WPRO
ABSTRACT
Pulmonary embolism (PE) is a serious clinical problem in patients with acquired risk factor such as cancer, immobilization, recent trauma and surgery. However PE may occur in hereditary thrombophilia like protein S deficiency which is caused by PROS1 gene mutation. The author reports a case of pulmonary embolism in a 33-year-old man with protein S deficiency and PROS1 gene mutation. Genetic analysis of the patient showed mutation 1063C→T in exon 10 of PROS1 gene, resulting in a substitution of arginine by cystine at position 355 (R355C).
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Arginine
/
Pulmonary Embolism
/
Exons
/
Risk Factors
/
Protein S Deficiency
/
Thrombophilia
/
Cystine
/
Immobilization
نوع الدراسة:
Etiology_studies
/
Risk_factors_studies
المحددات:
Adult
/
Humans
اللغة:
Ko
مجلة:
Keimyung Medical Journal
السنة:
2014
نوع:
Article