Ahmed Valve Implantation with Adjunctive Mitomycin C and 5-Fluorouracil: Outcomes at 2 Years
Journal of the Korean Ophthalmological Society
; : 1470-1477, 2011.
Article
ي Ko
| WPRIM
| ID: wpr-200328
المكتبة المسؤولة:
WPRO
ABSTRACT
PURPOSE:
To evaluate the outcomes of Ahmed valve implantation in neovascular glaucoma patients who received intraoperative mitomycin C (MMC) and postoperative 5-fluorouracil (5-FU) after 24 months of follow-up.METHODS:
A total of 40 eyes from 40 patients with neovascular glaucoma who received antiglaucomatous medication without previous glaucoma surgery were included in the present study. The patients were divided into 2 groups. The control group (20 eyes) underwent Ahmed valve implantation only and the study group (20 eyes) underwent Ahmed valve implantation and received intraoperative MMC and postoperative 5-FU. Failure was defined as the first occurrence of any of the following 1) the first of 3 consecutive visits where intraocular pressure (IOP) was over 18 mmHg; 2) 20% IOP reduction from baseline; 3) the final number of topical medications was not reduced by at least two from baseline; 4) the need for additional surgery; or 5) the occurrence of a serious complication.RESULTS:
In the control group, the cumulative success rate was 19.1% at 24 months. The cumulative success rate in the study group was 43.7% at 24 months. Serious complications such as endophthalmitis, valve exposure, or prolonged hypotony were not observed.CONCLUSIONS:
The adjunctive use of intraoperative MMC and postoperative 5-FU with Ahmed valve implantation resulted in a high success rate and good IOP control and did not cause serious complications during the follow-up period.Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Glaucoma
/
Glaucoma, Neovascular
/
Endophthalmitis
/
Follow-Up Studies
/
Mitomycin
/
Eye
/
Fluorouracil
/
Intraocular Pressure
نوع الدراسة:
Observational_studies
/
Prognostic_studies
المحددات:
Humans
اللغة:
Ko
مجلة:
Journal of the Korean Ophthalmological Society
السنة:
2011
نوع:
Article