Deflazacort for Type-1 Autoimmune Hepatitis in a Korean Girl
Journal of Korean Medical Science
; : 758-760, 2006.
Article
ي En
| WPRIM
| ID: wpr-211994
المكتبة المسؤولة:
WPRO
ABSTRACT
Prednisone or prednisolone are the mainstay drug treatments for autoimmune hepatitis in children. However, long-term use of corticosteroid is associated with the risk of steroid-induced toxicities, and this situation requires newer immuno-suppressive agents for the treatment of autoimmune hepatitis, especially in growing children. An 11-yr-old Korean girl with type-1 autoimmune hepatitis discontinued prednisolone due to toxicities, i.e., hirsutism, buffalo hump, and skin striae, and remained clinical and biochemical remission under replacement of deflazacort and ursodeoxycholic acid combination therapy. A follow-up liver biopsy after 19 months of deflazacort and ursodeoxycholic acid treatment showed histologic remission.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Pregnenediones
/
Ursodeoxycholic Acid
/
Cholagogues and Choleretics
/
Treatment Outcome
/
Hepatitis, Autoimmune
/
Drug Therapy, Combination
/
Immunosuppressive Agents
/
Korea
المحددات:
Child
/
Female
/
Humans
البلد/الأقليم حسب الموضوع:
Asia
اللغة:
En
مجلة:
Journal of Korean Medical Science
السنة:
2006
نوع:
Article