Clinical Research Progress on Transformed Lymphoma -Review / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 1232-1236, 2016.
Article
ي Zh
| WPRIM
| ID: wpr-246785
المكتبة المسؤولة:
WPRO
ABSTRACT
Histologic transformation (HT) is a frequent event in the clinical course of patients with indolent lymphoma with dismal outcome. The diagnosis of HT is based on clinical manifestation, PET-CT and pathologic biopsy, and the latter is a golden standard for HT. There are contradictory data about the impact of initial management on the risk of transformation. Patients who present with HT did not receive R-CHOP or chemotherapy-naive, should receive this regimen. For the subset of patients received R-CHOP prior to HT, the second line chemotherapy for DLBCL should be adopted. Consolidation with HDT-ASCT should be considered for the suitable young patients. The radio-immunotherapy and novel drugs showed a bright perspective for the patients with HT.
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Lymphoma, Non-Hodgkin
/
Antineoplastic Combined Chemotherapy Protocols
المحددات:
Humans
اللغة:
Zh
مجلة:
Journal of Experimental Hematology
السنة:
2016
نوع:
Article