Researches on the polymorphism of cytochrome P450 2A6 / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 424-427, 2002.
Article
ي Zh
| WPRIM
| ID: wpr-248531
المكتبة المسؤولة:
WPRO
ABSTRACT
Cytochrome P450 2A6(CYP2A6) is known as a major enzyme responsible for C-oxidation of nicotine and 7-hydroxylation of coumarin. The article reviews different alleles of CYP2A6 that have been discovered, their effect on CYP 2A6 activity and the relationship between genetic polymorphism of CYP2A6 and smoking behavior as well as susceptibility of lung and esophageal cancer in different individuals.
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Polymorphism, Genetic
/
Research
/
Esophageal Neoplasms
/
Aryl Hydrocarbon Hydroxylases
/
Smoking
/
Genetic Predisposition to Disease
/
Cytochrome P-450 CYP2A6
/
Genetics
/
Mixed Function Oxygenases
/
Lung Neoplasms
المحددات:
Humans
اللغة:
Zh
مجلة:
Chinese Journal of Medical Genetics
السنة:
2002
نوع:
Article