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Thrombocytopenia and its related factors: a hospital-based, cross-sectional study
Article ي En | WPRIM | ID: wpr-253641
المكتبة المسؤولة: WPRO
ABSTRACT
<p><b>INTRODUCTION</b>The objective of this study was to explore the association between thrombocytopenia and its related factors.</p><p><b>MATERIALS AND METHODS</b>This was a hospital-based, cross-sectional study. We retrospectively analysed the medical records of all patients who received periodic health examinations at a medical centre located at Taichung in Taiwan between 2000 and 2004. In all, 5585 subjects were included for further analysis. A complete physical examination, laboratory survey and abdominal ultrasonography were performed on each subject. The t-test, chi-square test and multivariate logistic regression analysis were used.</p><p><b>RESULTS</b>The subjects consisted of 3123 men (55.9%) and 2462 women (44.1%). The mean age was 49.4 +/- 12.3 years (range, 20 to 87). The overall prevalence of thrombocytopenia was found to be 0.5%, higher in men than in women (0.6% vs 0.4%, P = 0.504). After controlling for the other covariates, multivariate logistic regression analysis exhibited that the factors significantly related to thrombocytopenia were increasing age (OR, 1.04; 95% CI, 1.004-1.08), anti-HCV positive (OR, 5.24; 95% CI, 2.08-13.20), liver cirrhosis (OR, 7.93; 95% CI, 2.28-27.62), and splenomegaly (OR, 18.86; 95% CI, 6.86-51.87).</p><p><b>CONCLUSION</b>It is advisable to further check the hepatic status, if thrombocytopenia is noted.</p>
الموضوعات
النص الكامل: 1 الفهرس: WPRIM الموضوع الرئيسي: Splenomegaly / Taiwan / Thrombocytopenia / Blood / Odds Ratio / Epidemiology / Prevalence / Cross-Sectional Studies / Retrospective Studies / Age Factors نوع الدراسة: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies المحددات: Adult / Aged / Aged80 / Female / Humans / Male البلد/الأقليم حسب الموضوع: Asia اللغة: En مجلة: Ann. Acad. Med. Singap. (Online) السنة: 2010 نوع: Article
النص الكامل: 1 الفهرس: WPRIM الموضوع الرئيسي: Splenomegaly / Taiwan / Thrombocytopenia / Blood / Odds Ratio / Epidemiology / Prevalence / Cross-Sectional Studies / Retrospective Studies / Age Factors نوع الدراسة: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies المحددات: Adult / Aged / Aged80 / Female / Humans / Male البلد/الأقليم حسب الموضوع: Asia اللغة: En مجلة: Ann. Acad. Med. Singap. (Online) السنة: 2010 نوع: Article