A study of calcitonin gene-related peptide-immunoreactive nerve fibers of rat molar pulp during traumatic occlusion and after removal / 中华口腔医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the effect of traumatic occlusion on CGRP-immunoreactive (CGRP-IR) nerve fibres in rat molar pulp and observe the recovery of CGRP-IR nerve fibres after removal of traumatic occlusion.</p><p><b>METHODS</b>To observe immunohistochemically the change of CGRP-IR nerve fibres in molar pulp during traumatic occlusion and after removal.</p><p><b>RESULTS</b>The increase of number, density and morphology of CGRP-IR nerve fibres in traumatic occlusion group was more than in control group, however, the changes of CGRP-IR nerve fibres in removal of traumatic occlusion group were less than in control group.</p><p><b>CONCLUSIONS</b>The changes of CGRP-IR nerve fibres in number, morphology, and density are induced by traumatic occlusion in rat molar pulp, however, the nerve fibres recover to normal by removal of traumatic occlusion.</p>