Analysis of polymorphisms of mitochondrial DNA in 3 ethnic groups of Guizhou / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 626-631, 2013.
Article
ي Zh
| WPRIM
| ID: wpr-254547
المكتبة المسؤولة:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To analyze the population genetics characteristics of mitochondrial DNA (mtDNA) in Gelao, Mulao, Maonan ethnic groups from Guizhou.</p><p><b>METHODS</b>Minisequenceing and restriction fragment length polymorphism (RFLP) were used to analyze 12 single nucleotide polymorphism (SNPs) of mitochondrial DNA in the 3 ethnic groups.</p><p><b>RESULTS</b>A total of 30 haplotypes were detected in 156 samples. The distribution of H1, H23 had differed between Mulao, Maonan and Gelao, respectively, and so did M7 among the three groups. The difference was statistically significant (P < 0.05). Mulao, Maonan had respectively differed from Gelao and the difference was also statistically significant (P < 0.05).</p><p><b>CONCLUSION</b>There was a great similarity in the distribution of haplotypes of the mtDNA among the three ethnic groups, except for some difference in the distribution of certain haplotypes.</p>
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Pedigree
/
Polymorphism, Genetic
/
DNA, Mitochondrial
/
China
/
Asian People
/
Ethnology
/
Genetics
المحددات:
Humans
/
Male
البلد/الأقليم حسب الموضوع:
Asia
اللغة:
Zh
مجلة:
Chinese Journal of Medical Genetics
السنة:
2013
نوع:
Article