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The influence of tumor cells spreading in blood to relapse and distant metastasis of hepatocellular carcinoma after surgery / 中华外科杂志
Zhonghua Wai Ke Za Zhi ; (12): 1583-1585, 2008.
Article ي Zh | WPRIM | ID: wpr-258320
المكتبة المسؤولة: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the relationship between peripheral blood hepatocellular carcinoma cells-associated AFP mRNA and tumor relapse and metastasis.</p><p><b>METHODS</b>To detect several blood samples from the HCC patients by nested RT-PCR to find out AFP mRNA after 24 h, 72 h and one week and 4 weeks after surgery, and followed up the HCC patients for 1, 2, 3 years.</p><p><b>RESULTS</b>There were 7 patients occurred relapse or distant metastasis in 12 patients with AFP mRNA positive (7/12, 58.3%), there were 5 patients occurred relapse in 19 patients with AFP mRNA negative (5/19, 26.3%) within 1 year, there was 4 patients occurred relapse in second year (9/19, 47.3%); 5 patients occurred relapse in third year (10/19, 52.6%). Obvious connection between patients AFP mRNA positive and AFP mRNA negative was observed (P < 0.01).</p><p><b>CONCLUSIONS</b>HCC with AFP mRNA positive has more change to be recurrent compared with HCC patients with AFP mRNA negative.</p>
الموضوعات
النص الكامل: 1 الفهرس: WPRIM الموضوع الرئيسي: Pathology / Postoperative Period / General Surgery / Blood / RNA, Messenger / Alpha-Fetoproteins / Follow-Up Studies / Carcinoma, Hepatocellular / Genetics / Liver Neoplasms نوع الدراسة: Observational_studies / Prognostic_studies المحددات: Adult / Female / Humans / Male اللغة: Zh مجلة: Zhonghua Wai Ke Za Zhi السنة: 2008 نوع: Article
النص الكامل: 1 الفهرس: WPRIM الموضوع الرئيسي: Pathology / Postoperative Period / General Surgery / Blood / RNA, Messenger / Alpha-Fetoproteins / Follow-Up Studies / Carcinoma, Hepatocellular / Genetics / Liver Neoplasms نوع الدراسة: Observational_studies / Prognostic_studies المحددات: Adult / Female / Humans / Male اللغة: Zh مجلة: Zhonghua Wai Ke Za Zhi السنة: 2008 نوع: Article