Association between the number of retrieved lymph nodes in stage II( colorectal cancer radical resection and its prognosis / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
; (12): 260-262, 2010.
Article
ي Zh
| WPRIM
| ID: wpr-259302
المكتبة المسؤولة:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the association between the number of retrieved lymph nodes and the prognosis of stage II colorectal cancer.</p><p><b>METHODS</b>Clinical data of 380 patients with stage II colorectal cancer were analyzed retrospectively. SPSS 13.0 was used for data processing. Survival rate was calculated by Kaplan-Meier method, and risk factors related to prognosis of stage II colorectal cancer were analyzed by Logistic regression analysis. Recurrence rate and survival rate were assessed with Chi-squared test.</p><p><b>RESULTS</b>The average number of lymph nodes retrieved from 56 patients who developed recurrence or metastasis in 5 year after surgery was 9.5, and 16.3 from patients who had no recurrence or no metastasis(P<0.01). The number retrieved from 97 patients who died in 5 years after surgery was 11.1, and 16.7 from survivors. Patients were divided into 2 groups>or=12 group and <12 group. The 5-year survival rate was 83.9% in >or= 12 group and 62.0% in < 12 group, respectively(P<0.01), the recurrence rate was 6.4% in >or=12 group and 25.7% in < 12 group (P<0.01). The univariable analysis showed that the number of retrieved lymph nodes was significantly associated with the survival and recurrence in patients with stage II colorectal cancer (P<0.05).</p><p><b>CONCLUSIONS</b>The number of retrieved lymph nodes is associated with the prognosis of stage II colorectal cancer. Patients with more retrieved lymph nodes have a higher survival rate.</p>
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Pathology
/
Prognosis
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General Surgery
/
Colorectal Neoplasms
/
Retrospective Studies
/
Diagnosis
/
Lymph Node Excision
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Lymph Nodes
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Lymphatic Metastasis
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Neoplasm Staging
نوع الدراسة:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
المحددات:
Humans
اللغة:
Zh
مجلة:
Chinese Journal of Gastrointestinal Surgery
السنة:
2010
نوع:
Article