Studies on the lignans from Patrinia scabra / 药学学报

ABSTRACT

<p><b>AIM</b>To study the lignans from Patrinia scabra Bunge.</p><p><b>METHODS</b>The constituents were separated and purified by column chromatography with silical gel, RP-silical gel and Sephadex LH-20. Their structures were identified on the basis of spectral data (IR, MS, 1HNMR, 13CNMR, HMQC and HMBC).</p><p><b>RESULTS AND CONCLUSION</b>A new lignan was obtained and its structure was elucidated as 4-[1-ethoxyl-1-(4-hydroxy-3-methoxy)benzyl]methyl- 2-(4-hydroxy-3-methoxy)benzyl-3-hydroxymethyl-tetrahydro-furan (2), along with three known lignans, lariciresinol (1), isolariciresinol (3) and nortracheloside (4).</p>