Curative effect of stereotactic 186Re endocavitary irradiation on cystic craniopharyngioma / 中华肿瘤杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the treatment results of stereotactic (186)Re intracavitary irradiation in the patients with craniopharyngioma.</p><p><b>METHODS</b>Nineteen patients were treated with stereotactic (186)Re intracavitary irradiation, including 12 males and 7 females (average age, 37.2 years). Among them 12 patients had a solitary cyst, whereas 7 patients with mixed structure (e.g., a large cyst with a small solid portion). The mean volume of the cystic portion of the tumor before irradiation was 8390 mm(3).</p><p><b>RESULTS</b>The patients were followed up for 6 months to 3 years. The retraction of the cyst was complete in 7 patients, cyst volume decreased more than 50% in 5 patients and less than 50% in 7 cases. Among the 8 patients with visual acuity deficit before irradiation, 5 were improved. No hypopituitarism occurred in patients with normal pituitary function before treatment. One of the 4 patients with hypopituitarism was improved, 3 of the 5 patients with diabetes insipidus was improved.</p><p><b>CONCLUSION</b>Stereotactic (186)Re endocavitary irradiation for the treatment of cystic craniopharyngioma is a safe and effective procedure.</p>