Optimization of matrix formulation of effective parts cataplasm of Pogostemon cablin by uniform design / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 638-641, 2008.
Article
ي Zh
| WPRIM
| ID: wpr-295469
المكتبة المسؤولة:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To optimize the matrix formulation of the effective part Cataplasm of Pogostemon Cablin.</p><p><b>METHOD</b>The optimal preparation prescription was selected by U17 (17(11)) uniform design,and the tacking strength, cohesive strength and transdermal speed constant were used as test indexes. The equations of three test indexes were established by SPSS. With analysis of the contribution of factors by SPSS regression, the optimal matrix formulation was acquired.</p><p><b>RESULT</b>The optimal matrix formulation is carbopol U10-NoveriteTM7s-glycerine-sorbitol-kaolin-citric acid-aluminum trichloride (1.05.0202.02.00.250.2).</p><p><b>CONCLUSION</b>The matrix has good adhesive property, proper drug release rate, desirable hemocompatibility with the extractions of Pogostemon cablin.</p>
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Skin Absorption
/
Volatilization
/
Biocompatible Materials
/
Drugs, Chinese Herbal
/
Chemistry
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Chemistry, Pharmaceutical
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Adhesiveness
/
Regression Analysis
/
Lamiaceae
/
Metabolism
نوع الدراسة:
Diagnostic_studies
اللغة:
Zh
مجلة:
China Journal of Chinese Materia Medica
السنة:
2008
نوع:
Article