Chemical constituents from Corydalis yanhusuo / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents from the 60% ethanol extract of Corydalis yanhusuo.</p><p><b>METHOD</b>The chemical constituents were separated and purified by various chromatographic techniques, and their structures were elucidated by chemical evidence and spectroscopic analysis.</p><p><b>RESULT</b>Nine alkaloids were obtained and determined as 7-formyldidehydroglaucine (1), nantenine (2), (+)-O-methylbulbocapnine (3), d-corydaline (4), tetrahydrocoptisine (5), 8-oxocoptisine (6), palmatine (7), tetrahydropalmatine (8), and dehydrocorydaline (9), respectively.</p><p><b>CONCLUSION</b>Compound 1 was obtained from natural products for the first time, and its NMR data were firstly reported. Compound 3 was reported from Papaveraceae for the first time, and compound 6 was firstly reported from Corydalis yanhusuo.</p>