Prenatal diagnosis of single umbilical artery: implications for chromosomal abnormalities and neonatal outcome / 南方医科大学学报
Journal of Southern Medical University
; (12): 451-453, 2013.
Article
ي Zh
| WPRIM
| ID: wpr-322025
المكتبة المسؤولة:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the implications of a prenatal diagnosis of single umbilical artery (SUA) for chromosomal abnormalities and neonatal outcomes.</p><p><b>METHODS</b>From January, 2008 to June, 2012, color Doppler ultrasound identified 44 fetuses with SUA. Prenatal diagnoses with amniocentesis or umbilical blood sampling were subsequently ordered for routine chromosome karyotyping and the newborns were followed up for assessing the neonatal outcomes.</p><p><b>RESULTS</b>Of all the 44 fetuses, 24 had uncomplicated SUA, and 20 had other concurrent abnormalities (including 8 with abnormal ultrasound soft indexes and 12 with chromosomal abnormalities). The two groups of fetuses showed significant differences in gestational weeks at delivery and incidence of chromosomal abnormalities but not in neonatal weight, placenta weight or APGAR score.</p><p><b>CONCLUSIONS</b>Fetuses with a prenatal diagnosis of SUA and other development abnormities need to undergo prenatal chromosomal examination. For fetuses with uncomplicated SUA, careful ultrasound examination is necessary to avoid missed diagnosis of potential congenital abnormalities.</p>
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Pregnancy Trimester, Second
/
Pregnancy Trimester, Third
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Congenital Abnormalities
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Diagnostic Imaging
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Ultrasonography, Prenatal
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Chromosome Disorders
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Single Umbilical Artery
/
Fetus
/
Genetics
/
Karyotyping
نوع الدراسة:
Diagnostic_studies
/
Prognostic_studies
المحددات:
Adult
/
Female
/
Humans
/
Pregnancy
اللغة:
Zh
مجلة:
Journal of Southern Medical University
السنة:
2013
نوع:
Article