Study on the changes of thrombosis-associated factors in patients with coronary heart disease of turbidity-phlegm blocking syndrome / 中国结合医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To preliminarily explore the relationship between thrombosis and its associated factors in patients with coronary heart disease (CHD) of turbidity-phlegm blocking syndrome (TPB), and to study its acting mechanism.</p><p><b>METHODS</b>Plasma levels of thrombosis-associated factors, including Von Willebrand factor (vWF), D-dimer, and fibrinogen (Fg), in 85 patients of CHD with TPB, 93 with CHD of non-TPD, and 89 healthy persons were detected and compared.</p><p><b>RESULTS</b>Levels of the three factors were increased in all the CHD patients, and were higher in TPB patients than in non-TPB patients (P<0.01 or P<0.05).</p><p><b>CONCLUSION</b>The TPB syndrome in CHD patients was closely related to the blood coagulation-fibrinolytic system; they might be in pre-thrombosis state, and the plasma levels of vWF, D-dimer, and Fg could be taken as the objective indices for thrombosis differentiation of TPB syndrome in CHD patients.</p>