Analysis of prognostic factors in gastrointestinal stromal tumors of the small intestine / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
; (12): 213-216, 2005.
Article
ي Zh
| WPRIM
| ID: wpr-345204
المكتبة المسؤولة:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore the prognostic factors in patients with gastrointestinal stromal tumors of the small intestine.</p><p><b>METHODS</b>Tumor slides stained with hematoxylin and eosin from these patients were reviewed. Two histomorphologically representative areas were identified and arrayed on a tissue microarray. Immunohistochemistry staining were performed using antibodies to detect the expression of c-kit protein (CD117), CD34, smooth muscle actin, desmin, S-100, Ki-67, P53 and bcl-2 protein. The relationship between clinicopathologic features and prognosis was analyzed by univariate analysis.</p><p><b>RESULTS</b>The 1-, 3-, 5-year survival rate of 58 such patients were 98.3%, 69.7%, and 50.9% respectively. The prognosis was related with tumor size and gender by univariate analysis (P< 0.05).</p><p><b>CONCLUSION</b>More attention should be paid to the male patients with small intestine stromal tumors,especially those with tumors size> 5 cm, because those tumors are more likely to metastasize than smaller tumors (< or = 5 cm).</p>
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Pathology
/
Prognosis
/
Immunohistochemistry
/
Gastrointestinal Stromal Tumors
/
Diagnosis
/
Intestinal Neoplasms
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Intestine, Small
نوع الدراسة:
Diagnostic_studies
/
Prognostic_studies
المحددات:
Adult
/
Aged
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Female
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Humans
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Male
اللغة:
Zh
مجلة:
Chinese Journal of Gastrointestinal Surgery
السنة:
2005
نوع:
Article