Efficacy comparison of laparoscopy and open resection for gastrointestinal stromal tumor at the esophagogastric junction / 中华胃肠外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To compare the clinical outcomes between laparoscopy and open resection for gastrointestinal stromal tumor at the esophagogastric junction.</p><p><b>METHODS</b>Clinicopathological data of 42 patients with gastrointestinal stromal tumor (GIST) of esophagogastric junction undergoing resection in our department between October 2004 and October 2014 were retrospectively analyzed. Among them, 22 patients underwent laparoscopic resection (LR group) and 20 patients underwent open resection (OR group). Short-term efficacy and long-term outcomes were compared between the two groups.</p><p><b>RESULTS</b>There were no significant differences between the two groups in common data of patients. The recovery time in the LR group was significantly shorter than that in the OR group, including bowel function recovery, ambulation, resumption of oral intake, and postoperative hospital stay (all P<0.05). The incidence of postoperative complications in the LR group was lower than that in the OR group(0 vs. 10%, P=0.221). Meanwhile difference of 5-year disease-free-survival between the two groups (LR 100% vs. OR 89%, P=0.384) was not statistically significant.</p><p><b>CONCLUSION</b>Laparoscopic resection for gastrointestinal stromal tumor at the esophagogastric junction is superior to open resection in short-term efficacy, and similar to open resection in long-term outcomes.</p>