A study of aspermia-related genes by genchips and analysis of the RAP1A gene / 中华男科学杂志
National Journal of Andrology
; (12): 654-657, 2003.
Article
ي Zh
| WPRIM
| ID: wpr-357117
المكتبة المسؤولة:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the differential gene expression profiles between the normal and aspermia human testes by genechips.</p><p><b>METHODS</b>Probes were prepared from mRNA extracted from both normal and aspermia testes and employed on Biostar H-40s genechips to detect the differential gene expression profiles. A distinctly up-regulated gene RAP1A was analyzed by bibliogrphic retrieval.</p><p><b>RESULTS</b>Six hundred and twenty-three differential expressed genes were found, among which the distinctly up-regulated gene RAP1A was closely related to human sperm regulation.</p><p><b>CONCLUSIONS</b>Screening the differential gene expression profiles between the normal and aspermia human testes by genechips can be used in the study of aspermia-related genes.</p>
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Oligospermia
/
Oligonucleotide Array Sequence Analysis
/
Rap1 GTP-Binding Proteins
/
Gene Expression Profiling
/
Genetics
/
Methods
المحددات:
Adult
/
Humans
/
Male
اللغة:
Zh
مجلة:
National Journal of Andrology
السنة:
2003
نوع:
Article