The Effectiveness of Silodosin for Nocturnal Polyuria in Elderly Men With Benign Prostatic Hyperplasia: A Multicenter Study / 대한배뇨장애요실금학회지
International Neurourology Journal
; : 190-196, 2015.
Article
ي En
| WPRIM
| ID: wpr-41792
المكتبة المسؤولة:
WPRO
ABSTRACT
PURPOSE: To investigate improvement in nocturia and nocturnal polyuria in nocturnal polyuria patients after silodosin administration by using a 3-day frequency volume chart. METHODS: This was a prospective multicenter study. We enrolled nocturnal polyuria patients (nocturnal polyuria index [NPi]>0.33), aged > or =60 years, diagnosed with the 3-day frequency volume charts of patients with benign prostatic hyperplasia taking alpha-blockers. Of the 54 patients, 30 (55.6%) completed the study according to the study protocol (per-protocol group), and 24 dropped out (dropout group). RESULTS: Of the 24 patients in the dropout group, 5 withdrew consent due to side effects or lack of efficacy, 7 were lost to follow-up at 4 weeks, 8 were lost to follow-up at 12 weeks, and 4 dropped out due to failure to complete 3-day frequency volume charts at 12 weeks. In the per-protocol group, there was significant improvement in the International Prostate Symptom Score (IPSS), especially question numbers 1, 3, 4, 5, 6, 7, and the quality of life question (P=0.001, P=0.007, P0.33. Considering the high dropout rate of our study due to no implementation of 3-day frequency volume charts, prospective and large-scale studies are needed to confirm our results.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Patient Dropouts
/
Polyuria
/
Prostate
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Prostatic Hyperplasia
/
Quality of Life
/
Prospective Studies
/
Adrenergic alpha-Antagonists
/
Nocturia
/
Lost to Follow-Up
نوع الدراسة:
Clinical_trials
/
Guideline
/
Observational_studies
المحددات:
Aged
/
Humans
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Male
اللغة:
En
مجلة:
International Neurourology Journal
السنة:
2015
نوع:
Article