Treatment of Condyloma Acuminatum with Imiquimod Cream:A Randomized,Double-blind,Place-bo-controlled,Multi-central Clinical Trial / 中华皮肤科杂志
Chinese Journal of Dermatology
; (12)2003.
Article
ي Zh
| WPRIM
| ID: wpr-521215
المكتبة المسؤولة:
WPRO
ABSTRACT
Objective To observe the clinical efficacy and safety of5%imiquimod cream in the top-ical treatment of condyloma acuminatum(CA).Methods A randomized,double-blind,parallel placebo-controlled clinical study was conducted.The test drug was topically used in CA patients,three times a week for8weeks.Patients whose warts cleared completely were followed up for one month to determine recurrence rates.Results Two hundred fifty-eight patients with anogenital warts were enrolled into this trial.One hun-dred twenty-nine patients were randomly selected to receive5%imiquimod cream;129patients were ran-domly chosen to receive placebo cream.Results showed that the cure rates were12.30%,32.79%,50%,60.66%respectively in study group for2,4,6,8weeks and were4.88%,14.63%,19.51%,26.02%respec-tively in control group for2,4,6,8weeks(P
النص الكامل:
1
الفهرس:
WPRIM
نوع الدراسة:
Clinical_trials
اللغة:
Zh
مجلة:
Chinese Journal of Dermatology
السنة:
2003
نوع:
Article