Preparation of Irisquinone freeze-drying Injection and its stability / 中成药
Chinese Traditional Patent Medicine
; (12)1992.
Article
ي Zh
| WPRIM
| ID: wpr-574615
المكتبة المسؤولة:
WPRO
ABSTRACT
AIM: To prepare the irisquinone freeze-drying injection and investigate its stability. METHODS: The degradation pattern of irisquinone and its effects were measured. At the same time, the stability of freeze-(drying) injection by classic thermostatical test. RESULTS: Irisquinone solution was unstable to heat and its content decreased remarkably in acid and alkaline solutions. The result showed that oil/water partition coeffecient of irisquinone was very large. The irisquinone-hydropropyl1-?-cyclodextrin inclusion complex freeze-drying injection was very effective to enhance the drug stability. CONCLUSION: Irisquinone inclusion complex injection has character of good stability.
النص الكامل:
1
الفهرس:
WPRIM
اللغة:
Zh
مجلة:
Chinese Traditional Patent Medicine
السنة:
1992
نوع:
Article