Study of the relationship between plasma resistin level and insulin resistance in the patients with cerebrovascular disease / 临床神经病学杂志

ABSTRACT

Objective To investigate the relationship between plasma resistin level and insulin resistance in the patients with cerebrovascular disease.Methods Fasting plasma resistin and insulin (INS) protein levels were determined by ELISA method in 50 patients with atherothrombotic cerebral infarction (ACI), 36 patients with lacunar infarction (LI), 36 patients with intracerebral hemorrhage (ICH) and 46 healthy control subjects. Blood glucose, blood lipid, blood pressure, height and weight were measured. Body mass index (BMI) and quantitative insulin sensitivity check index (QUICKI) were caculated as well.Results Compared with the control subjects, there were significantly higher fasting plasma insulin protein level and lower QUICKI in the ACI and ICH patients ( P