Safety evaluation for medical ozone oil on skin / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 131-138, 2018.
Article
ي Zh
| WPRIM
| ID: wpr-693787
المكتبة المسؤولة:
WPRO
ABSTRACT
Objective:
To evaluate skin irritation,acute toxicity,and allergy of medical ozone oil for clinical application.Methods:
In contrast to their left and right side irritation,one or more skin irritation tests were performed on the intact and damaged skins of guinea pigs.With the maximum concentration,acute skin toxicity test was applied on the intact and damaged skins of rats.Active cutaneous anaphylaxis was applied to the guinea pigs.Results:
High concentration (ozone consumption150 g/L) of medical ozone oil showed a slight irritation on the broken skin of guinea pigs,while low concentrations did not show skin irritation.Medical ozone oil had no obvious acute toxicity to rats.The medical ozone oil and base oil showed mildallergy for the skin of guinea pig.Conclusion:
The irritation of medical ozone oil is related to its concentration.With appropriateconcentration and duration of treatment,medical ozone oil is safe.
النص الكامل:
1
الفهرس:
WPRIM
اللغة:
Zh
مجلة:
Journal of Central South University(Medical Sciences)
السنة:
2018
نوع:
Article