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Efficacy of combination of ozonated water with oil for treatment of tinea pedis / 中南大学学报(医学版)
Zhongnan Daxue xuebao. Yixue ban ; (12): 147-151, 2018.
Article ي Zh | WPRIM | ID: wpr-693790
المكتبة المسؤولة: WPRO
ABSTRACT
Objective:To evaluate efficacy of combined therapy with ozonated water and oil on patients with tinea pedis.Methods:A total of 60 patients with tinea pedis were divided into 2 groups in a randomized and blinded test.Patients in a control group were treated with naftinfine hydrochloride and ketoconazole cream once a day.Patients in an ozone group were treated with ozonated water bath and then ozonated oil topical application once a day.Patients in the 2 groups were treated for 4 weeks.Clinical and laboratory data were collected for both groups at the end of the 1st week,the 2nd week,and the 4th week.The Pearson chi-square was performed to compare scores of the clinical signs and symptoms (CSS) and the mycological result between the 2 groups.Independent samples T-test was performed to compare the curative effect between the 2 groups.Results:After 4 weeks' treatment,6 patients were positive in the control group determined by mycological examination while 1 patient was positive in the ozone group,with no significant difference between the 2 groups (P>0.05).Changes in CSS at the end of the 1st week,2nd week,and 4th week were obtained and showed no significant difference between the 2 groups at the 3 different time points (P>0.05).No side effects were observed.Conclusion:Combination of ozonated water with oil is effective on treatment oftinea pedis and it shows no side effects.
Key words
النص الكامل: 1 الفهرس: WPRIM نوع الدراسة: Clinical_trials اللغة: Zh مجلة: Zhongnan Daxue xuebao. Yixue ban السنة: 2018 نوع: Article
النص الكامل: 1 الفهرس: WPRIM نوع الدراسة: Clinical_trials اللغة: Zh مجلة: Zhongnan Daxue xuebao. Yixue ban السنة: 2018 نوع: Article