Progress in Diagnosis and Treatment of Primary Biliary Cholangitis / 胃肠病学

ABSTRACT

In the past 40 years,patients with primary biliary cholangitis (PBC)have benefited from the extensive use of ursodeoxycholic acid (UDCA),resulting in increase of response rate and survival rate. The prognosis of PBC patients was significantly improved. However,some patients responded poorly to UDCA and with poor long-term outcome. Therefore,accurate diagnosis,evaluation and risk stratification based on serological and pathological characteristics of the patients are very important for the treatment of PBC. This article summarized the progress in diagnosis and treatment of PBC.