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A Concomitant Hemato-Oncologic Disorder of Patient with Down Syndrome
Article ي Ko | WPRIM | ID: wpr-715121
المكتبة المسؤولة: WPRO
ABSTRACT
A patient with Down syndrome has hematologic and oncologic disorders of medical complication. Down syndrome shows that characteristic hematologic and oncologic abnormalities and developments of disorders are different at ages. Many hematologic disorders were related to Down syndrome. There are diseases of red blood cells, white blood cell disorders, platelet and bleeding disorders, aplastic anemia, and transient myeloproliferative disease. Acute myeloid leukemia, acute lymphoblastic leukemia, and rarely solid tumors (Neuroblastoma, Wilm's tumor, Hodgkin's lymphoma) are also associated with Down syndrome. We checked clinical manifestations of each disorder and we should make standard hematologic index of different age groups. In addition, the relations between chromosome 21 and hemato-oncologic disorders should be found. We need to investigate potential therapeutic interventions that can improve quality of life and life expectancy in patients with Down syndrome.
الموضوعات
Key words
النص الكامل: 1 الفهرس: WPRIM الموضوع الرئيسي: Quality of Life / Blood Platelets / Chromosomes, Human, Pair 21 / Leukemia, Myeloid, Acute / Life Expectancy / Down Syndrome / Wilms Tumor / Erythrocytes / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Hemorrhage المحددات: Humans اللغة: Ko مجلة: Soonchunhyang Medical Science السنة: 2018 نوع: Article
النص الكامل: 1 الفهرس: WPRIM الموضوع الرئيسي: Quality of Life / Blood Platelets / Chromosomes, Human, Pair 21 / Leukemia, Myeloid, Acute / Life Expectancy / Down Syndrome / Wilms Tumor / Erythrocytes / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Hemorrhage المحددات: Humans اللغة: Ko مجلة: Soonchunhyang Medical Science السنة: 2018 نوع: Article