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Membranoproliferative glomerulonephritis in a patient with chronic brucellosis
Article ي En | WPRIM | ID: wpr-717208
المكتبة المسؤولة: WPRO
ABSTRACT
Brucellosis is the most common zoonotic disease in Greece, with an endemic distribution and can affect any organ. Infiltration of the renal parenchyma causes acute and chronic interstitial nephritis with granulomas, whereas renal glomeruli are rarely affected. The disease has been sporadically reported, and it causes various histopathologic patterns. Herein, we describe the case of a 39-year-old stock breeder with a history of recurrent episodes of bacteremia caused by Brucella melitensis over a period of 3 years. Two months after the last episode of bacteremia, he presented with mild renal insufficiency, nephrotic range proteinuria, and microscopic hematuria. A renal biopsy revealed membranoproliferative glomerulonephritis with a pattern of focal-segmental nodular sclerosis and moderate tubulointerstitial fibrosis. The patient received antimicrobial and corticosteroid therapy with partial remission of the nephrotic syndrome.
الموضوعات
Key words
النص الكامل: 1 الفهرس: WPRIM الموضوع الرئيسي: Proteinuria / Sclerosis / Biopsy / Fibrosis / Brucellosis / Glomerulonephritis, Membranoproliferative / Zoonoses / Bacteremia / Brucella melitensis / Renal Insufficiency المحددات: Adult / Humans البلد/الأقليم حسب الموضوع: Europa اللغة: En مجلة: Kidney Research and Clinical Practice السنة: 2018 نوع: Article
النص الكامل: 1 الفهرس: WPRIM الموضوع الرئيسي: Proteinuria / Sclerosis / Biopsy / Fibrosis / Brucellosis / Glomerulonephritis, Membranoproliferative / Zoonoses / Bacteremia / Brucella melitensis / Renal Insufficiency المحددات: Adult / Humans البلد/الأقليم حسب الموضوع: Europa اللغة: En مجلة: Kidney Research and Clinical Practice السنة: 2018 نوع: Article