A Case of Ethosuximide-Induced Aplastic Anemia Successfully Treated with Methylprednisolone Pulse Therapy / 임상소아혈액종양
Clinical Pediatric Hematology-Oncology
; : 175-179, 2018.
Article
ي En
| WPRIM
| ID: wpr-717637
المكتبة المسؤولة:
WPRO
ABSTRACT
Aplastic anemia may develop secondary to environmental exposure to entities such as chemicals, medical drugs, and infectious agents. Fatal complications from antiepileptic medications may occur despite careful and appropriate use. We report the case of a 9-year-old girl with a presenting diagnosis of aplastic anemia following treatment with ethosuximide for absence seizures. Aplastic anemia can now be cured with stem cell transplantation or immunosuppressive therapy. In this case, however, because of the impossibility of bone marrow transplantation and the specific needs of the patient's parents, three courses of methylprednisolone pulse therapy were administered. Following the therapy, there was improvement in pancytopenia and complete remission in the bone marrow. No adverse side effects of therapy were observed. The authors suggest that methylprednisolone pulse therapy may be a treatment for acquired aplastic anemia.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Pancytopenia
/
Parents
/
Bone Marrow
/
Methylprednisolone
/
Bone Marrow Transplantation
/
Epilepsy, Absence
/
Stem Cell Transplantation
/
Diagnosis
/
Environmental Exposure
/
Ethosuximide
نوع الدراسة:
Diagnostic_studies
المحددات:
Child
/
Female
/
Humans
اللغة:
En
مجلة:
Clinical Pediatric Hematology-Oncology
السنة:
2018
نوع:
Article