Long-term survival in a patient with acute promyelocytic leukemia with isolated meningeal relapse
Korean Journal of Hematology
; : 208-210, 2010.
Article
ي En
| WPRIM
| ID: wpr-720389
المكتبة المسؤولة:
WPRO
ABSTRACT
The meningeal involvement is rare in acute promyelocytic leukemia. We experienced a 39-year-old woman who achieved complete remission with all-trans retinoic acid, idarubicin and cytarabine therapy. Several months later, she complained of non-specific headache. Her complete blood cell count was normal, but magnetic resonance image of brain revealed focal meningeal enhancement and cerebrospinal fluid showed leukemic promyelocytes and PML/RARA rearrangement. Bone marrow study showed hematologic, cytogenetic and molecular remission. She was treated with intrathecal and systemic chemotherapy and whole brain radiotherapy. The patient has survived for 68 months since the last systemic chemotherapy.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Recurrence
/
Tretinoin
/
Blood Cell Count
/
Bone Marrow
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Brain
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Magnetic Resonance Spectroscopy
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Idarubicin
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Leukemia, Promyelocytic, Acute
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Cytarabine
/
Cytogenetics
المحددات:
Adult
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Female
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Humans
اللغة:
En
مجلة:
Korean Journal of Hematology
السنة:
2010
نوع:
Article