Report of 3 Cases of Hairy Cell Leukemia Treated with 2-Chlorodeoxyadenosine / 대한혈액학회지
Korean Journal of Hematology
; : 292-296, 2002.
Article
ي Ko
| WPRIM
| ID: wpr-720962
المكتبة المسؤولة:
WPRO
ABSTRACT
Hairy cell leukemia (HCL) is an uncommon chronic B-cell lymphoproliferative disorder characterized by cytopenia, splenomegaly and mononuclear cells displaying cytoplasmic projections. Diagnosis is based on the distinctive hairy cell morphology and immunological profile. In the last 10 to 15 years the prognosis of patients with HCL has improved considerably following the use of purine analogues such as deoxycoformycin and 2-chlorodeoxyadenosine (2-CdA). We report 3 patients with HCL who were treated with 2-CdA at a daily dosage of 0.1mg/kg by continuous intravenous infusion for 7 days. After 1 or 2 courses of treatment, all patients achieved complete remission and are still alive in disease-free status.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Prognosis
/
Splenomegaly
/
Infusions, Intravenous
/
B-Lymphocytes
/
Leukemia, Hairy Cell
/
Pentostatin
/
Cladribine
/
Cytoplasm
/
Diagnosis
/
Lymphoproliferative Disorders
نوع الدراسة:
Diagnostic_studies
/
Prognostic_studies
المحددات:
Humans
اللغة:
Ko
مجلة:
Korean Journal of Hematology
السنة:
2002
نوع:
Article