The change of coronary circulating TNF-α level in patients with coronary heart disease after PTCA and its significance / 第二军医大学学报
Academic Journal of Second Military Medical University
; (12): 185-186, 2001.
Article
ي Zh
| WPRIM
| ID: wpr-736832
المكتبة المسؤولة:
WPRO
ABSTRACT
Objective:
To observe the effect of percutaneous tr ansluminal coronary angioplasty (PTCA) on coronary circulating tumor necrosis fa ctor-α (TNF-α) activity.Methods:
Plasma TNF-α levls were measured with radioimmunoassay and bioactive assay respectively. Result s Plasma TNF-α activity in femoral artery (AO) was significantly incr eased immediately after PTCA [(15.86±3.75) U/ml vs (41.32±4.36) U/ml, P<0.01], and plasma TNF-α activity in coronary sinus was remarkably incre ased immediately after PTCA [(16.72±4.14) U/ml vs (65.61±6.25) U/ml, P<0.01]. There was no change in plasma TNF-α activity in AO 24 h after PT CA [(18.32±5.12) U/ml vs (15.86±3.75) U/ml, P>0.05]. Conclu sion The increase in plasma TNF-α activity after PTCA may be associat ed with the injury of coronary artery caused by PTCA, suggesting that TNF-α ma y be involved in the coronary occlusion and the development of coronary restenos is after PTCA.
النص الكامل:
1
الفهرس:
WPRIM
اللغة:
Zh
مجلة:
Academic Journal of Second Military Medical University
السنة:
2001
نوع:
Article