Mass spectrometry-based proteomic approaches to study pathogenic bacteria-host interactions
Protein & Cell
; (12): 265-274, 2015.
Article
ي En
| WPRIM
| ID: wpr-757598
المكتبة المسؤولة:
WPRO
ABSTRACT
Elucidation of molecular mechanisms underlying host-pathogen interactions is important for control and treatment of infectious diseases worldwide. Within the last decade, mass spectrometry (MS)-based proteomics has become a powerful and effective approach to better understand complex and dynamic host-pathogen interactions at the protein level. Herein we will review the recent progress in proteomic analyses towards bacterial infection of their mammalian host with a particular focus on enteric pathogens. Large-scale studies of dynamic proteomic alterations during infection will be discussed from the perspective of both pathogenic bacteria and host cells.
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Pathology
/
Mass Spectrometry
/
Bacteria
/
Bacterial Infections
/
Bacterial Proteins
/
Virulence
/
Chemistry
/
Protein Processing, Post-Translational
/
Proteomics
/
Host-Pathogen Interactions
المحددات:
Animals
/
Humans
اللغة:
En
مجلة:
Protein & Cell
السنة:
2015
نوع:
Article