Visual Field Defect after Taking Atorvastatin/Ezetimibe, a Case Study
Korean Journal of Clinical Pharmacy
; : 133-137, 2019.
Article
ي Ko
| WPRIM
| ID: wpr-759613
المكتبة المسؤولة:
WPRO
ABSTRACT
Atorvastatin is one of the most widely prescribed medications for dyslipidemia treatment. In Korea, post combined therapy with ezetimibe, a 73-year-old woman was reported by a community pharmacy to have experienced visual field defect, which recovered after drug discontinuation. She had never experienced this symptom before, and several studies have reported an association between use of statins and visual disorders such as blurred vision, diplopia, and cataract. Blockage of cholesterol accumulation, oxidative stress, or myopathy is expected to be a cause of this symptom. Naranjo scale, Korean causality assessment algorithm (Ver.2), and World Health Organization-Uppsala Monitoring Center (WHO-UMC) criteria were the three tools used to determine causality between the visual disorder and atorvastatin. The results represent ‘probable’, ‘certain’, and ‘probable/likely’ causality, respectively. Our results, in combination with a review of literature, indicate that ocular adverse effects are highly likely related to atorvastatin.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Pharmacies
/
Vision Disorders
/
Cataract
/
Visual Fields
/
Cholesterol
/
Global Health
/
Oxidative Stress
/
Hydroxymethylglutaryl-CoA Reductase Inhibitors
/
Diplopia
/
Drug-Related Side Effects and Adverse Reactions
المحددات:
Aged
/
Female
/
Humans
البلد/الأقليم حسب الموضوع:
Asia
اللغة:
Ko
مجلة:
Korean Journal of Clinical Pharmacy
السنة:
2019
نوع:
Article