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Frozen Cytology of Meningeal Malignant Solitary Fibrous Tumor/Hemangiopericytoma
Article ي En | WPRIM | ID: wpr-766016
المكتبة المسؤولة: WPRO
ABSTRACT
A 51-year-old woman presented with severe dizziness. The brain magnetic resonance image revealed a 5.5 cm multiloculated mass with a thick rim in the left temporal lobe. Cytological examination of frozen diagnosis of the mass showed hypercellular sheets of round and rhabdoid cells in a hemorrhagic background, and two mitotic figures were observed. Histologically, the excised dura-based mass consisted of predominantly round cells with small foci of rhabdoid tumor cells in a pseudoalveolar pattern in a hemorrhagic background, and the cells showed nuclear positivity for signal transducer and activator of transcription 6 as well as frequent mitosis. The mass was diagnosed as a grade 3 solitary fibrous tumor (SFT)/hemangiopericytoma (HPC). The cytological diagnosis of SFT/HPC is challenging because of the heterogeneous cytological findings, such as histological heterogeneity, and because there are no standardized cytological criteria for malignant SFT/HPC. Cytological findings, such as singly scattered small cells, hypercellularity, rare ropy collagen, and round and rhabdoid cells with pseudoalveolar pattern, may assist in the diagnosis of malignant SFT/HPC.
الموضوعات
Key words
النص الكامل: 1 الفهرس: WPRIM الموضوع الرئيسي: Temporal Lobe / Population Characteristics / Brain / Central Nervous System / Collagen / Rhabdoid Tumor / Diagnosis / Dizziness / STAT6 Transcription Factor / Solitary Fibrous Tumors نوع الدراسة: Diagnostic_studies المحددات: Female / Humans اللغة: En مجلة: Journal of Pathology and Translational Medicine السنة: 2019 نوع: Article
النص الكامل: 1 الفهرس: WPRIM الموضوع الرئيسي: Temporal Lobe / Population Characteristics / Brain / Central Nervous System / Collagen / Rhabdoid Tumor / Diagnosis / Dizziness / STAT6 Transcription Factor / Solitary Fibrous Tumors نوع الدراسة: Diagnostic_studies المحددات: Female / Humans اللغة: En مجلة: Journal of Pathology and Translational Medicine السنة: 2019 نوع: Article