Testosterone Undecanoate Pills improves insulin resistance in type-2 diabetes men with hypogonadism / 中华男科学杂志
National Journal of Andrology
; (12): 517-521, 2017.
Article
ي Zh
| WPRIM
| ID: wpr-812732
المكتبة المسؤولة:
WPRO
ABSTRACT
Objective@#To evaluate the effects of Testosterone Undecanoate Pills (TUP) on insulin resistance (IR) in type-2 diabetes men with hypogonadism.@*METHODS@#We randomly divided 82 type-2 diabetes patients with hypogonadism into a treatment (n = 42) and a control group (n = 40), both maintaining their glucose- and lipid-reducing therapies, while the former treated orally with TUP in addition. After 6 months of medication, we compared the body mass index (BMI), waist circumference (WC), blood glucose level, HbA1c, lipid profile, IR index obtained by homeostatic model assessment (HOMA-IR), insulin sensitivity index (ISI), sex hormone levels, and sexual function scores between the two groups of patients.@*RESULTS@#Compared with the baseline, the patients in the treatment group showed significant decreases after medication in BMI ([26.71 ± 2.39] vs [25.15 ± 2.28] kg/m2, P 0.05).@*CONCLUSIONS@#TUP can significantly improve insulin resistance in type-2 diabetes men with hypogonadism.
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Testosterone
/
Blood
/
Blood Glucose
/
Glycated Hemoglobin
/
Insulin Resistance
/
Body Mass Index
/
Therapeutic Uses
/
Diabetes Mellitus, Type 2
/
Drug Therapy
/
Waist Circumference
نوع الدراسة:
Prognostic_studies
المحددات:
Humans
/
Male
اللغة:
Zh
مجلة:
National Journal of Andrology
السنة:
2017
نوع:
Article