Experimental study of spirulina platensis in treating allergic rhinitis in rats / 中南大学学报(医学版)

ABSTRACT

OBJECTIVE@#To determine the therapeutic effect of spirulina platensis in allergic rhinitis (AR).@*METHODS@#Ovalbumin sensitized white rats used as AR animals were treated with spirulina platensis (SPP). At the end of the treatment, the differences in the behavior science were observed; the changes in the nasal mucosa and mast cell degranulation were studied pathologically; and the levels of serum histamine and total immunoglobulin (Ig) E were determined by enzyme-linked immune sorbent assay.@*RESULTS@#The behavior science score of the SPP treatment group was lower than that of the negative control group (P 0.05 ).@*CONCLUSION@#Spirulina platensis can prevent and treat AR in rats, which implies the possibility of using spirulina platensis for AR patients in the future.